Ionic EquilibriumMedium
Question
The pKa of acetyl salicylic acid (aspirin) is 3.5. The pH of gastric juice in human stomach is about 2-3 and the pH in the smal intestine is about 8. Aspirin will be :
Options
A.unionised in the smal intestine and in the stomach
B.Completely ionised in the small intestine and in the stomach
C.ionised in the stomach and almost unionised in the small intestine
D.ionised in the small intestine and almost unionised in the stomach
Solution
Being weak acid, it will be almost completely ionized in intestine (alkaline medium) while almost unionised in stomach (acidic medium ).
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