Ionic EquilibriumHard

Question

The pKa of acetylasliclic acid (aspirin) is 3.5. The pH of gastric juice in human stomach is about 2-3 and the pH in the small intestine is about 8. Aspirin will be:

Options

A.Unionised in the small intestine and in the stomach
B.Completely ionised in the small intestine and in the stomach
C.Ionised in the stomach and almost unisonised in the small intestine
D.Ionised in the small intestine and almost unionized in the stomach

Solution

Aspirin a weak acid is unionised in acid medium due to common ion effect and completely ionised in alkaline medium.

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