Principle of Inheritance and VariationEasyBloom L3
Question
In human sex determination the key factor is
Options
A.Y-chromosome
B.Both a) and c)
C.X-chromosome
D.None of these
Solution
Sol.(a) [Key Concept: Human Sex Determination — Y Chromosome] In human sex determination, the KEY factor is the Y chromosome. The Y chromosome carries the SRY gene (sex-determining region Y) which encodes the testis-determining factor (TDF). When SRY is present and expressed, the indifferent gonad develops into testes, triggering male development. Without Y (XX), ovaries develop → female. Individuals with XXY (Klinefelter's) are male (Y present); XO (Turner's) are female (no Y present). The Y chromosome is the primary sex determinant in humans.
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