Principle of Inheritance and VariationEasyBloom L3
Question
Drosophila flies with XXY genotype are females but in case of humans, such individuals are abnormal males (Klinefelter's syndrome). This indicates that
Options
A.The Y chromosome has no role in sex determination
B.In Drosophila, the Y chromosome is essential for sex determination
C.The Y chromosome is male determining in humans
D.The Y chromosome is female determining in Drosophila
Solution
Sol.(c) [Key Concept: Sex Determination — Y Chromosome Role] The different outcomes in Drosophila (XXY = female) versus humans (XXY = Klinefelter's syndrome, abnormal male) indicate that the Y chromosome is MALE-DETERMINING in humans. In humans, the Y chromosome carries the SRY (sex-determining region Y) gene that triggers male development regardless of the number of X chromosomes. In Drosophila, sex is determined by the ratio of X chromosomes to autosomes (X:A ratio), not the Y chromosome.
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