Principle of Inheritance and VariationHard

Question

Sickle cell anaemia is

Options

A.an autosomal ilked dominant trait
B.caused by substitution of valine by glutamic acid in the -globin chain of haemomglobin
C.caused by a change in base pair of DNA
D.characterized by elongated sickle like RBCs with a nucleus

Solution

Sickle cell anaemia is caused by a change in a single base pair of DNA. It is a genetic disease reported from megroes. The individuals of sickle cell anaemia are immune to malaria.

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