Molecular Basis of InheritanceMedium
Question
Which of the following statement is correct regarding the process of replication in E.coli?
Options
A.The DNA dependent DNA polymerase catalyses polymerization in $5^{'} \rightarrow 3^{'}$ as well as $3^{'} \rightarrow 5^{'}$ direction
B.The DNA dependent DNA polymerase catalyses polymerization in $5^{'} \rightarrow 3$ ' direction
C.The DNA dependent DNA polymerase catalyses polymerization in one direction that is $3^{'} \rightarrow 5^{'}$
D.The DNA dependent RNA polymerase catalyses polymerization in one direction, that is $5^{'} \rightarrow 3^{'}$
Solution
Sol. [Key Concept: Direction of DNA synthesis]
During DNA replication in E. coli, DNA dependent DNA polymerase adds nucleotides to a growing DNA strand in the 5′→3′ direction. It reads its template in the opposite direction. Hence, option (2). Option (4) describes RNA synthesis, including the chemistry used by primase, rather than extension of the new DNA strand by DNA polymerase.
Create a free account to view solution
View Solution FreeMore Molecular Basis of Inheritance Questions
Telocentric chromosome differs from acro centric chromosome in having :-...Genes are packaged into a bacterial chromo-some by...One gene-one enzyme hypothesis was postulated by...Experimental material in the study of DNA replication has been...′Signal hypothesis′ for the biosynthesis of secretory type of proteins was proposed by...