Principle of Inheritance and VariationMediumBloom L1

Question

The incorrect statement with regard to Haemophilia is: [NEET 2013]

Options

A.It is a recessive disease
B.It is a dominant disease
C.A single protein involved in the clotting of blood is affected
D.It is a sex-linked disease

Solution

Sol.(b) [Key Concept: Haemophilia — Recessive Not Dominant] Haemophilia is NOT a dominant disease — it is an X-LINKED RECESSIVE disease. Option (b) is the incorrect statement. Correct facts: (a) it IS recessive (males with one Xh allele are affected; females need two Xh alleles); (c) a single clotting protein is affected (Factor VIII in haemophilia A, Factor IX in haemophilia B); (d) it IS sex-linked (X-linked). Haemophilia's X-linked recessive pattern explains its higher prevalence in males.

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