Principle of Inheritance and VariationMediumBloom L3

Question

If two persons with 'AB' blood group marry and have sufficiently large number of children these children could be classified as 'A' blood group: 'AB' blood group: 'B' blood group in 1 : 2 : 1 ratio. Modern technique of protein electrophoresis reveals presence of both 'A' and 'B' type proteins in 'AB' blood group individuals. This is an example of:

Options

A.incomplete dominance
B.Partial dominance
C.Complete cominance
D.Codominance

Solution

Sol.(d) [Key Concept: Codominance — ABO Blood Groups AB] This is CODOMINANCE. AB blood group individuals (I^A I^B genotype) express BOTH A and B antigens simultaneously on their red blood cells — both alleles are fully and independently expressed in the heterozygote. Protein electrophoresis confirms the presence of both A and B proteins. Cross: I^A I^B × I^A I^B → 1/4 I^A I^A (A) : 2/4 I^A I^B (AB) : 1/4 I^B I^B (B) = 1A:2AB:1B. This differs from incomplete dominance (where a new intermediate phenotype appears).

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