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Question

Identify the incorrect statement about tertiary structure of proteins.

Options

A.They can be fibrous or globular in structure.
B.The main forces that stabilize the structure are hydrogen bonding, disulphide links, van der Waals and electrostatic forces of attraction.
C.The structure remains intact when exposed to pH changes.
D.A linear polypeptide chain will convert to a secondary structure and then further folding of the secondary structure will convert to tertiary structure.

Solution

Sol. [Key Concept: Tertiary protein structure is disrupted by pH change (it is not pH-stable), so that statement is the incorrect one.]

On changing pH tertiary strutcure of protein disrupted and amino acids intact only by peptide linkage.

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