Cell: The Unit of LifeHard

Question

An enzymes of TCA cycle are locted in the mitochondrial matrix except one which is located in inner mitochondrial me,brane in eukaryotes and in cytosol in prokaryotes. This enzyme is

Options

A.Succinate dehydrogenase
B.Lactate dehydrogenase
C.Isocitrate dehydrogenase
D.Malate dehydrogenase

Solution

All the oxidative enzymes of TCA are located in matrix except succinic dehydragenase. This enzyme catalysed the conversion of sucinic catalysed the conversion of succinic into funaric acid. The enzyme is an integral protin complex that is tightly bound to the inner mitochondrial membrane.Infact this enzyme for inner membranes when doing mitochondrial fractionations.

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