Microbes in Human WelfareHard
Question
Antigen binding site in an antibody is found between
Options
A.two light chains
B.two heavy chains
C.one heavy and one light chain
D.either between two light chains or between one heavy and one light chains or between one the nature of antigen
Solution
Antigen binding site in an antibody is found either between two light chains or between one heavy andone light chains one between heavy and one light chain depending upon the nature of antigen. There are five type of mammalian Ig heavy chain denoted by the Greek letters: α, δ, ε, γ, and μ The type of heavy chain present defines the class of antibody; these chains are found in IgA,IgD, IgE, IgG, and IgM antibodies, respectively. Distinct heavy chains differ in size and composition; and contain approximately 450 amino acids, while and have approximately 550 amino acids. Each heavy chain has two region, the constant region and the varigion and the variale region. Alight chin has two successive domains:one constant domain and one variable domain. The approximate lenght of a light chian is 211to 217 amino acids. each antibody contains two light chain that are alwys identical; only one type of light chain, κ or λ is present per antibody in mammals.
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