Chemical Coordination and IntegrationHard

Question

Addison′s disease result from

Options

A.hyposecrection of gonads
B.hyposecrection of adrenal gland
C.hypertrophy of kidney
D.hyposecrection of pituitary gland

Solution

Addison′s disease occurs due to hyposecretion of both mineralocorticoids and glucocorticoids (cortisol) from the layers of adrenal cortex called zona glomerula and zona fasciculata repectively. the Disease is characterized by excessive loss of Na+, Cl- and HCO3 increased K+ level in blood, weight loss, muscle weakness, fatigue, low blood, pressure, and somtimes darkening of the skin in both exposed and nonexposed parts of the body.

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