JEE Main | 2018Chemical BondingHard

Question

The predominant form of histamine present in human blood is (pKa, Histidine = 6.0)

Options

A.

B.

C.

D.

Solution

Structure of Histamine 

Blood is slightly basic in nature (7.35 pH) approx.
At this pH terminal NH2 will get protonated due to more basic nature.
∴ Predominant structure of Histamine is

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