Molecular Basis of InheritanceMedium
Question
During transciption holoenxyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. Whae is that sequence celled ?
Options
A.CAAT box
B.GGTT box
C.AAAT box
D.TATA box
Solution
TATA box is present in eukaryotic promoter region. It has a resemblance with Pribnow box of prokaryotes. TATA box was identified by Dr. Hogness and so, it is also called as Hogness box. It is a 7 bp long region located 20 bp upstream to the start point. During the process of tran scription the RNA polymerase (a holoenzyme which has a core unit and a sigma factor forproper initiatipn of transcription) binds to TATA box due to which DNA assumes a saddle like structure at this place.
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