Molecular Basis of InheritanceHard
Question
The telomeres of eukaryotic chromosomes consist of short sequences of
Options
A.thymine rich repeats
B.cytosine rich repeats
C.adenine rich repeats
D.guanine rich repeats
Solution
Telomeres have been shown to have unique steuctures that include short nucleotide sequencences present as tandemly repeated units. The basic repeat sequence im all the species studied has the pattern 5′ - T1 - 4A0 - 1G1 - 8 - 3′. Same repeated sequence is found in at the end of all chromosomes in a species. Not only this same telomere sequence may occur in widely divergent specirs (eg, Human beings, Neurospora and som acellular slime molds). Clusters of G residues in one strand and C residues in the other characterize telomeric DNA. Also, in some species the telomeres terminate with a single-stranded DNA (12-16 nucleotides long) rich in guanine.
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