Principle of Inheritance and VariationMedium

Question

Which base is responsible for hot spots for spontaneous point mutations ?

Options

A.Guanine
B.Adenine
C.5-bromouracil
D.5-methylcytosine

Solution

The term ″hot spots″ was used by Benzer for the sites which are more mutable than other sites. Studies in 1978 revealed that 5-methyl cytosine resine residues occur at the position of each hot spot.

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