Principle of Inheritance and VariationHard
Question
The most striking example of point mutation is found in a disease called
Options
A.thalassemia
B.night blindness
C.Down′s syndrome
D.sickle cell anaemia
Solution
Sickle cell disease is a genetic disease reported from negroes due to a molecular mutation of gene HbA on chromosome 11 which produces β-chain of adult gaemoglobin.
In this disease nucleotide triplet CTC is changed to CAC, these changes takes place at a particular point of chromosome, so they are called as point mutation.
In this disease nucleotide triplet CTC is changed to CAC, these changes takes place at a particular point of chromosome, so they are called as point mutation.
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