Breathing and Exchange of GasesHard

Question

Which two of the following changes (1 - 4) usually tends to occur in the plain dwellers when the move to high altitudes (3,500 m or more ) ?
(1) Increase in red blood cell size
(2) Increase in red blood cell production
(3) Increase in breathing rate
(4) Increase in thrmobocyte count

Options

A.(2) and (3)
B.(3) and (4)
C.(1) and (4)
D.(1) and (2)

Solution

When a person moves to higher altitudes, the Po2 and total atmospheric pressure decrease. Hypoxia stimulates the JG-cells of the kidney to release erythropoietin harmone, wich stimulates erythopoesis in bone marrow causing polycythemia. Hypoxia will also increase breathing rate. Initially the size of RBCs will also increase but with increase in number of RBCs, the size of RBCs becomes normal.

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